EGFR Protein (AA 669-1210, Leu858Arg-Mutant, Thr790Met-Mutant) (GST tag)

Catalog No. ABIN5570677

Product Details

Target: EGFR (Epidermal Growth Factor Receptor (EGFR))

Protein Type: Recombinant

Biological Activity: Active

Protein Characteristics: AA 669-1210, Leu858Arg-Mutant, Thr790Met-Mutant

Origin: Human

Source: Insect cells (Sf21)

Purification tag / Conjugate: This EGFR protein is labelled with GST tag.

Application: SDS-PAGE (SDS), Functional Studies (Func)

Purpose: EGFR (T790M/L858R) (Human) Recombinant Protein

Characteristics: Human EGFR (NP_005219.2, 669 a.a. - 1210 a.a.) T790M/L858R mutant parial recombinant protein with GST tag expressed in Baculovirus infected Sf21 cells.
This product with activity data is belong to bioactive protein.

Purification: Baculovirus infected insect cell (Sf21) expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Baculovirus infected insect cell (Sf21) expression system
Product Quality tested by: Loading 1 ug protein in SDS-PAGE

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05 % Brij35, 1 mM DTT, 10 % glycerol)

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Target Details

Target: EGFR (Epidermal Growth Factor Receptor (EGFR))

Alternative Name: EGFR (EGFR Products)

Synonyms: C-erb Protein, CG10079 Protein, D-EGFR Protein, D-Egf Protein, DEGFR Protein, DER Protein, DER flb Protein, DER/EGFR Protein, DER/faint little ball Protein, DER/top Protein, DER/torpedo Protein, DER1 Protein, DEgfr Protein, Degfr Protein, Der Protein, DmHD-33 Protein, Dmel\\CG10079 Protein, EFG-R Protein, EGF-R Protein, EGFR Protein, EGFr Protein, EGfr Protein, EK2-6 Protein, Egf Protein, Egf-r Protein, EgfR Protein, El Protein, Elp Protein, Elp-1 Protein, Elp-B1 Protein, Elp-B1RB1 Protein, HD-33 Protein, TOP Protein, Torpedo/DER Protein, Torpedo/Egfr Protein, c-erbB Protein, d-egf-r Protein, dEGFR Protein, dEGFR1 Protein, dEgfr Protein, der Protein, egfr Protein, flb Protein, l(2)05351 Protein, l(2)09261 Protein, l(2)57DEFa Protein, l(2)57EFa Protein, l(2)57Ea Protein, mor1 Protein, top Protein, top/DER Protein, top/flb Protein, torpedo/Egfr Protein, torpedo/egfr Protein, EGFR12 Protein, EGFR15 Protein, egfr1 Protein, Erbb2 Protein, ERBB Protein, ERBB1 Protein, HER1 Protein, PIG61 Protein, mENA Protein, ErbB-1 Protein, Errp Protein, 9030024J15Rik Protein, AI552599 Protein, Erbb Protein, Errb1 Protein, Wa5 Protein, wa-2 Protein, wa2 Protein, epidermal growth factor receptor Protein, Epidermal growth factor receptor Protein, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) Protein, EGFR Protein, Egfr Protein, egfra Protein, egfr1 Protein, LOC5564544 Protein

Background: Full Gene Name: epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Synonyms: ERBB,ERBB1,HER1,PIG61,mENA

Gene ID: 1956

Pathways: NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins