JAK2 Protein (Val617Phe-Mutant) (GST tag)
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- Target See all JAK2 Proteins
- JAK2 (Janus Kinase 2 (JAK2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Val617Phe-Mutant
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Origin
- Human
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Source
- Insect cells (Sf21)
- Purification tag / Conjugate
- This JAK2 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS), Functional Studies (Func)
- Purpose
- JAK2 (V617F) (Human) Recombinant Protein
- Characteristics
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Human JAK2 (NP_004963.1, 532 a.a. - 1132 a.a.) V617F mutant partial recombinant protein with GST tag expressed in Baculovirus infected Sf21 cells.
This product with activity data is belong to bioactive protein. - Purification
- Baculovirus infected insect cell (Sf21) expression system
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Baculovirus infected insect cell (Sf21) expression system
Product Quality tested by: SDS-PAGE Stained with Coomassie Blue - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05 % Brij35, 1 mM DTT, 10 % glycerol)
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Aliquot to avoid repeated freezing and thawing.
- Storage
- -80 °C
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- Target
- JAK2 (Janus Kinase 2 (JAK2))
- Alternative Name
- JAK2 (JAK2 Products)
- Synonyms
- JAK2bCA Protein, jak2 Protein, JTK10 Protein, THCYT3 Protein, AI504024 Protein, C81284 Protein, Fd17 Protein, JAK-2 Protein, Janus kinase 2b Protein, Janus kinase 2 Protein, jak2b Protein, JAK2 Protein, Jak2 Protein
- Background
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Full Gene Name: Janus kinase 2 (a protein tyrosine kinase)
Synonyms: JTK10 - Gene ID
- 3717
- Pathways
- JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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