EIF3G Protein (AA 2-320) (His-SUMO Tag)

Catalog No. ABIN5709453

Product Details

Target: EIF3G (Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G))

Protein Type: Recombinant

Protein Characteristics: AA 2-320

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This EIF3G protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: PTGDFDSKPS WADQVEEEGE DDKCVTSELL KGIPLATGDT SPEPELLPGA PLPPPKEVIN GNIKTVTEYK IDEDGKKFKI VRTFRIETRK ASKAVARRKN WKKFGNSEFD PPGPNVATTT VSDDVSMTFI TSKEDLNCQE EEDPMNKLKG QKIVSCRICK GDHWTTRCPY KDTLGPMQKE LAEQLGLSTG EKEKLPGELE PVQATQNKTG KYVPPSLRDG ASRRGESMQP NRRADDNATI RVTNLSEDTR ETDLQELFRP FGSISRIYLA KDKTTGQSKG FAFISFHRRE DAARAIAGVS GFGYDHLILN VEWAKPSTN

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: EIF3G (Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G))

Alternative Name: EIF3G (EIF3G Products)

Synonyms: EIF3-P42 Protein, EIF3S4 Protein, eIF3-delta Protein, eIF3-p44 Protein, 44kDa Protein, D0Jmb4 Protein, Eif3s4 Protein, TU-189B2 Protein, p44 Protein, eif3s4 Protein, zgc:56553 Protein, eIF3g-A Protein, eif3s4-A Protein, eIF3g Protein, eIF3-S4 Protein, An16g05260 Protein, AO090011000648 Protein, eukaryotic translation initiation factor 3 subunit G Protein, eukaryotic translation initiation factor 3, subunit G Protein, eukaryotic translation initiation factor 3 subunit G S homeolog Protein, Eukaryotic translation initiation factor 3 subunit G Protein, eukaryotic translation initiation factor Protein, EIF3G Protein, Eif3g Protein, eif3g Protein, eif3g.S Protein, eif-3.G Protein, eIF3g Protein, ANI_1_732144 Protein, AOR_1_1112054 Protein, VDBG_00824 Protein, MGYG_08099 Protein, Tsp_04379 Protein

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassbly and recycling of post-termination ribosomal complexes and subsequently prevents prature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.

Molecular Weight: 51.46 kDa

UniProt: O75821

Pathways: Ribonucleoprotein Complex Subunit Organization