TNFL6 Protein (AA 130-281, Extracellular) (His tag)

Catalog No. ABIN5709501

Product Details

Target: TNFL6 (Tumor Necrosis Factor Ligand Superfamily Member 6 (TNFL6))

Protein Type: Recombinant

Protein Characteristics: Extracellular, AA 130-281

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This TNFL6 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: QIGHPSPPPE KKELRKVAHL TGKSNSRSMP LEWEDTYGIV LLSGVKYKKG GLVINETGLY FVYSKVYFRG QSCNNLPLSH KVYMRNSKYP QDLVMMEGKM MSYCTTGQMW ARSSYLGAVF NLTSADHLYV NVSELSLVNF EESQTFFGLY KL

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: TNFL6 (Tumor Necrosis Factor Ligand Superfamily Member 6 (TNFL6))

Alternative Name: TNFL6 (TNFL6 Products)

Background: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.

Molecular Weight: 21.4 kDa

UniProt: P48023