HIST1H2AG Protein (AA 2-130) (His tag)

Catalog No. ABIN5709657

Product Details

Target: HIST1H2AG (Histone Cluster 1, H2ag (HIST1H2AG))

Protein Type: Recombinant

Protein Characteristics: AA 2-130

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This HIST1H2AG protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: SGRGKQGGKA RAKAKTRSSR AGLQFPVGRV HRLLRKGNYA ERVGAGAPVY LAAVLEYLTA EILELAGNAA RDNKKTRIIP RHLQLAIRND EELNKLLGKV TIAQGGVLPN IQAVLLPKKT ESHHKAKGK

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: HIST1H2AG (Histone Cluster 1, H2ag (HIST1H2AG))

Alternative Name: H2A1 (HIST1H2AG Products)

Synonyms: H2A.1b Protein, H2A/p Protein, H2AFP Protein, H2AG Protein, pH2A/f Protein, histone cluster 1 H2A family member g Protein, histone H2A type 1 Protein, similar to Histone H2A type 1 Protein, HIST1H2AG Protein, LOC786163 Protein, LOC680322 Protein, LOC104968446 Protein

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.

Molecular Weight: 18.1 kDa

UniProt: P0C0S8