HNRH1 Protein (AA 2-449) (His-SUMO Tag)

Catalog No. ABIN5709677

Product Details

Target: HNRH1 (Heterogeneous Nuclear Ribonucleoprotein H (HNRH1))

Protein Type: Recombinant

Protein Characteristics: AA 2-449

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This HNRH1 protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: MLGTEGGEGF VVKVRGLPWS CSADEVQRFF SDCKIQNGAQ GIRFIYTREG RPSGEAFVEL ESEDEVKLAL KKDRETMGHR YVEVFKSNNV EMDWVLKHTG PNSPDTANDG FVRLRGLPFG CSKEEIVQFF SGLEIVPNGI TLPVDFQGRS TGEAFVQFAS QEIAEKALKK HKERIGHRYI EIFKSSRAEV RTHYDPPRKL MAMQRPGPYD RPGAGRGYNS IGRGAGFERM RRGAYGGGYG GYDDYNGYND GYGFGSDRFG RDLNYCFSGM SDHRYGDGGS TFQSTTGHCV HMRGLPYRAT ENDIYNFFSP LNPVRVHIEI GPDGRVTGEA DVEFATHEDA VAAMSKDKAN MQHRYVELFL NSTAGASGGA YEHRYVELFL NSTAGASGGA YGSQMMGGMG LSNQSSYGGP ASQQLSGGYG GGYGGQSSMS GYDQVLQENS SDFQSNIA

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: HNRH1 (Heterogeneous Nuclear Ribonucleoprotein H (HNRH1))

Alternative Name: HNRH1 (HNRH1 Products)

Background: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).

Molecular Weight: 65.1 kDa

UniProt: P31943