Id2 Protein (AA 1-134, full length) (His-SUMO Tag)
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- Target See all Id2 Proteins
- Id2 (Inhibitor of DNA Binding 2 (Id2))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-134
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Id2 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product Id2 Protein
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Inhibitor of DNA Binding 2 (Id2) (AA 1-134) protein (GST tag)
Id2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Inhibitor of DNA Binding 2 (Id2) (AA 1-67) protein (GST tag)Id2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Inhibitor of DNA Binding 2 (Id2) (AA 1-134) protein (Strep Tag)Crystallography grade Id2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Inhibitor of DNA Binding 2 (Id2) (AA 1-134) protein (Strep Tag)Crystallography grade Id2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Inhibitor of DNA Binding 2 (Id2) protein (Myc-DYKDDDDK Tag)Id2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Id2 (Inhibitor of DNA Binding 2 (Id2))
- Alternative Name
- ID2 (Id2 Products)
- Synonyms
- AI255428 Protein, C78922 Protein, Idb2 Protein, bHLHb26 Protein, Ac2-300 Protein, GIG8 Protein, ID2A Protein, ID2H Protein, XId2 Protein, id2-A Protein, inhibitor of DNA binding 2 Protein, inhibitor of DNA binding 2, HLH protein Protein, inhibitor of DNA binding 2 L homeolog Protein, Id2 Protein, ID2 Protein, id2.L Protein
- Background
- Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
- Molecular Weight
- 30.9 kDa
- UniProt
- Q02363
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