PCSK5 Protein (AA 117-452) (His-SUMO Tag)

Catalog No. ABIN5710073

Product Details

Target: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Protein Type: Recombinant

Protein Characteristics: AA 117-452

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PCSK5 protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: DYDLSHAQST YFNDPKWPSM WYMHCSDNTH PCQSDMNIEG AWKRGYTGKN IVVTILDDGI ERTHPDLMQN YDALASCDVN GNDLDPMPRY DASNENKHGT RCAGEVAATA NNSHCTVGIA FNAKIGGVRM LDGDVTDMVE AKSVSYNPQH VHIYSASWGP DDDGKTVDGP APLTRQAFEN GVRMGRRGLG SVFVWASGNG GRSKDHCSCD GYTNSIYTIS ISSTAESGKK PWYLEECSST LATTYSSGES YDKKIITTDL RQRCTDNHTG TSASAPMAAG IIALALEANP FLTWRDVQHV IVRTSRAGHL NANDWKTNAA GFKVSHLYGF GLMDAE

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Alternative Name: PCSK5 (PCSK5 Products)

Synonyms: PC5 Protein, PC6 Protein, PC6A Protein, SPC6 Protein, subtilase Protein, PC5/6A Protein, PC5A Protein, b2b1549Clo Protein, b2b585Clo Protein, Pc5 Protein, fur2 Protein, spc6 Protein, spc6A Protein, MGC98915 Protein, PCSK5 Protein, pc6 Protein, spc6a Protein, pcsk5 Protein, zgc:165659 Protein, proprotein convertase subtilisin/kexin type 5 Protein, proprotein convertase subtilisin/kexin type 5 S homeolog Protein, proprotein convertase subtilisin/kexin type 5b Protein, PCSK5 Protein, Pcsk5 Protein, pcsk5.S Protein, LOC528098 Protein, pcsk5 Protein, pcsk5b Protein

Background: Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins. Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif. May be responsible for the maturation of gastrointestinal peptides. May be involved in the cellular proliferation of adrenal cortex via the activation of growth factors .

Molecular Weight: 52.68 kDa

UniProt: Q04592

Pathways: Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones