PPM1B Protein (AA 2-193) (His-SUMO Tag)
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- Target See all PPM1B Proteins
- PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-193
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PPM1B protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MSIVLVCFSN APKVSDEAVK KDSELDKHLE SRVEEIMEKS GEEGMPDLAH VMRILSAENI PNLPPGGGLA GKRNVIEAVY SRLNPHRESD GASDEAEESG SQGKLVEALR QMRINHRGNY RQLLEEMLTS YRLAKVEGEE SPAEPAATAT SSNSDAGNPV TMQESHTESE SGLAELDSSN EDAGTKMSGE KI
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product PPM1B Protein
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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) (AA 1-192) protein (GST tag)
PPM1B Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) (AA 2-390) protein (His tag)Crystallography grade PPM1B Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) (AA 2-479) protein (His tag)Crystallography grade PPM1B Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PPM1B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PPM1B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PPM1B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))
- Alternative Name
- PPM1B (PPM1B Products)
- Synonyms
- PP2C-beta-X Protein, PP2CB Protein, PP2CBETA Protein, PPC2BETAX Protein, Pp2c2 Protein, fc18g04 Protein, ppm1a Protein, wu:fc18g04 Protein, zgc:92329 Protein, pp2c-beta-x Protein, pp2cb Protein, pp2cbeta Protein, ppc2betax Protein, zgc:92031 Protein, protein phosphatase, Mg2+/Mn2+ dependent 1B Protein, protein phosphatase 1B, magnesium dependent, beta isoform Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1B Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Bb Protein, protein phosphatase, Mg2+/Mn2+ dependent 1B L homeolog Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Ba Protein, PPM1B Protein, Ppm1b Protein, ppm1bb Protein, ppm1b.L Protein, ppm1ba Protein
- Background
- Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
- Molecular Weight
- 36.74 kDa
- UniProt
- O75688
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