PTGDS Protein (AA 23-190) (His-SUMO Tag)
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- Target See all PTGDS Proteins
- PTGDS (Prostaglandin D2 Synthase (PTGDS))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-190
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PTGDS protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- APEAQVSVQP NFQQDKFLGR WFSAGLASNS SWLREKKAAL SMCKSVVAPA TDGGLNLTST FLRKNQCETR TMLLQPAGSL GSYSYRSPHW GSTYSVSVVE TDYDQYALLY SQGSKGPGED FRMATLYSRT QTPRAELKEK FTAFCKAQGF TEDTIVFLPQ TDKCMTEQ
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product PTGDS Protein
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Prostaglandin D2 Synthase (PTGDS) (AA 23-190) protein (His tag)
PTGDS Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Prostaglandin D2 Synthase (PTGDS) (AA 1-190) protein (GST tag)PTGDS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Prostaglandin D2 Synthase (PTGDS) (AA 1-199) protein (GST tag)PTGDS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Prostaglandin D2 Synthase (PTGDS) (AA 25-189) protein (His tag)Crystallography grade PTGDS Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- PTGDS (Prostaglandin D2 Synthase (PTGDS))
- Alternative Name
- PTGDS (PTGDS Products)
- Synonyms
- 6PGD Protein, GSTS Protein, GSTS1-1 Protein, PGD2 Protein, PGDS Protein, L-PGDS Protein, LPGDS Protein, PDS Protein, PGDS2 Protein, H-PGDS Protein, Ptgds2 Protein, 21kDa Protein, Ptgs3 Protein, PH2DISO Protein, phosphogluconate dehydrogenase Protein, hematopoietic prostaglandin D synthase Protein, prostaglandin D2 synthase Protein, prostaglandin D2 synthase (brain) Protein, prostaglandin D synthase Protein, prostaglandin D2 synthase 21kDa (brain) Protein, PGD Protein, HPGDS Protein, PTGDS Protein, Hpgds Protein, Ptgds Protein, LOC100009453 Protein
- Background
- Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NR sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous syst and male reproductive syst.
- Molecular Weight
- 34.69 kDa
- UniProt
- P41222
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