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TANK Protein (AA 1-119, partial) (GST tag)

TANK Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5710452
  • Target See all TANK Proteins
    TANK (TRAF Family Member-Associated NFKB Activator (TANK))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-119, partial
    Origin
    • 6
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This TANK protein is labelled with GST tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV DIASAESSI
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product TANK Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    TANK (TRAF Family Member-Associated NFKB Activator (TANK))
    Alternative Name
    TANK (TANK Products)
    Synonyms
    I-TRAF Protein, ITRAF Protein, TRAF2 Protein, C86182 Protein, E430026L09Rik Protein, zgc:153048 Protein, i-traf Protein, tank Protein, traf2 Protein, TRAF family member associated NFKB activator Protein, TRAF family member-associated Nf-kappa B activator Protein, TRAF family member-associated NFKB activator Protein, TRAF family member associated NFKB activator L homeolog Protein, TANK Protein, Tank Protein, tank Protein, tank.L Protein
    Background
    Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Acts as a regulator of TRAF function by maintaining th in a latent state. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2.
    Molecular Weight
    41 kDa
    UniProt
    Q92844
    Pathways
    p53 Signaling, TLR Signaling, Activation of Innate immune Response
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