Tescalcin Protein (TESC) (AA 2-214) (His-SUMO Tag)
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- Target See all Tescalcin (TESC) Proteins
- Tescalcin (TESC)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-214
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Tescalcin protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- GAAHSASEEV RELEGKTGFS SDQIEQLHRR FKQLSGDQPT IRKENFNNVP DLELNPIRSK IVRAFFDNRN LRKGPSGLAD EINFEDFLTI MSYFRPIDTT MDEEQVELSR KEKLRFLFHM YDSDSDGRIT LEEYRNVVEE LLSGNPHIEK ESARSIADGA MMEAASVCMG QMEPDQVYEG ITFEDFLKIW QGIDIETKMH VRFLNMETMA LCH
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product TESC Protein
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Tescalcin (TESC) (AA 2-214) protein (His tag)
Crystallography grade TESC Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, Crys, WB
Tescalcin (TESC) (AA 2-214) protein (His tag)Crystallography grade TESC Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, Crys, WB
Tescalcin (TESC) protein (Myc-DYKDDDDK Tag)TESC Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Tescalcin (TESC)
- Alternative Name
- CHP3 (TESC Products)
- Synonyms
- TSC Protein, chp3 Protein, CHP3 Protein, 1010001A17Rik Protein, 2410011K10Rik Protein, TE-1 Protein, RGD1566317 Protein, tescalcin Protein, tescalcin L homeolog Protein, tesc Protein, TESC Protein, Tesc Protein, tesc.L Protein
- Background
- Functions as an integral cofactor in cell pH regulation by controlling plasma mbrane-type Na+/H+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma mbrane. Promotes the induction of hatopoietic st cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.
- Molecular Weight
- 40.6 kDa
- UniProt
- Q96BS2
- Pathways
- Proton Transport
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