TXNRD1 Protein (AA 1-497, partial) (His-SUMO Tag)
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- Target See all TXNRD1 Proteins
- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-497, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TXNRD1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MNGPEDLPKS YDYDLIIIGG GSGGLAAAKE AAQYGKKVMV LDFVTPTPLG TRWGLGGTCV NVGCIPKKLM HQAALLGQAL QDSRNYGWKV EETVKHDWDR MIEAVQNHIG SLNWGYRVAL REKKVVYENA YGQFIGPHRI KATNNKGKEK IYSAERFLIA TGERPRYLGI PGDKEYCISS DDLFSLPYCP GKTLVVGASY VALECAGFLA GIGLDVTVMV RSILLRGFDQ DMANKIGEHM EEHGIKFIRQ FVPIKVEQIE AGTPGRLRVV AQSTNSEEII EGEYNTVMLA IGRDACTRKI GLETVGVKIN EKTGKIPVTD EEQTNVPYIY AIGDILEDKV ELTPVAIQAG RLLAQRLYAG STVKCDYENV PTTVFTPLEY GACGLSEEKA VEKFGEENIE VYHSYFWPLE WTIPSRDNNK CYAKIICNTK DNERVVGFHV LGPNAGEVTQ GFAAALKCGL TKKQLDSTIG IHPVCAEVFT TLSVTKRSGA SILQAGC
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product TXNRD1 Protein
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Thioredoxin Reductase 1 (TXNRD1) (AA 161-647) (Active) protein (His tag)
TXNRD1 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, Func Active
Thioredoxin Reductase 1 (TXNRD1) (AA 1-497) protein (GST tag)TXNRD1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Thioredoxin Reductase 1 (TXNRD1) (AA 2-499) protein (His tag)TXNRD1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Thioredoxin Reductase 1 (TXNRD1) (AA 1-649) protein (Strep Tag)Crystallography grade TXNRD1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Thioredoxin Reductase 1 (TXNRD1) (AA 1-613) protein (Strep Tag)Crystallography grade TXNRD1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Thioredoxin Reductase 1 (TXNRD1) proteinTXNRD1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
- Alternative Name
- TRXR1 (TXNRD1 Products)
- Synonyms
- TrxR1 Protein, cb682 Protein, fb83a08 Protein, wu:fb83a08 Protein, GB14972 Protein, MGC85342 Protein, NADPH-dependent thioredoxin reductase C Protein, T32G6.20 Protein, T32G6_20 Protein, GRIM-12 Protein, TR Protein, TR1 Protein, TRXR1 Protein, TXNR Protein, Tr Protein, thioredoxin reductase 1 Protein, thioredoxin reductase 1 L homeolog Protein, NADPH-dependent thioredoxin reductase C Protein, ThioRedoXin Reductase Protein, TXNRD1 Protein, txnrd1 Protein, Trxr-1 Protein, txnrd1.L Protein, NTRC Protein, trxr-1 Protein, Txnrd1 Protein
- Background
- Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell mbrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
- Molecular Weight
- 58.61 kDa
- UniProt
- Q16881
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
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