WDR77 Protein (AA 1-312, partial) (His-SUMO Tag)
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- Target See all WDR77 Proteins
- WDR77 (WD Repeat Domain 77 (WDR77))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-312, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This WDR77 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MRKETPPPLV PPAAREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL FKDPCAAPNE GFCSAGVQTE AGVADLTWVG ERGILVASDS GAVELWELDE NETLIVSKFC KYEHDDIVST VSVLSSGTQA VSGSKDICIK VWDLAQQVVL SSYRAHAAQV TCVAASPHKD SVFLSCSEDN RILLWDTRCP KPASQIGCSA PGYLPTSLAW HPQQSEVFVF GDENGTVSLV DTKSTSCVLS SAVHSQCVTG LVFSPHSVPF LASLSEDCSL AVLDSSLSEL FRSQAHRDFV RDATWSPLNH SL
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product WDR77 Protein
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WD Repeat Domain 77 (WDR77) (AA 1-312) protein (His tag)
WDR77 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
WD Repeat Domain 77 (WDR77) (AA 1-342) protein (GST tag)WDR77 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
WD Repeat Domain 77 (WDR77) (AA 1-342) protein (Strep Tag)Crystallography grade WDR77 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
WD Repeat Domain 77 (WDR77) (AA 1-342) protein (Strep Tag)Crystallography grade WDR77 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- WDR77 (WD Repeat Domain 77 (WDR77))
- Alternative Name
- MEP50 (WDR77 Products)
- Synonyms
- MEP-50 Protein, MEP50 Protein, Nbla10071 Protein, RP11-552M11.3 Protein, p44 Protein, p44/Mep50 Protein, 2610003I18Rik Protein, 2610312E17Rik Protein, C79984 Protein, p44/MEP50 Protein, RGD1310479 Protein, mep50 Protein, valois Protein, WDR77 Protein, zgc:65780 Protein, zgc:77274 Protein, WD repeat domain 77 Protein, WD repeat domain 77 S homeolog Protein, WDR77 Protein, Wdr77 Protein, wdr77.S Protein, wdr77 Protein
- Background
- Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assbly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
- Molecular Weight
- 49.5 kDa
- UniProt
- Q9BQA1
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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