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FIL1d Protein (AA 1-155, full length) (His-SUMO Tag)

FIL1d Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5711795
  • Target See all FIL1d Proteins
    FIL1d (Interleukin 1 delta (FIL1d))
    Protein Type
    Recombinant
    Protein Characteristics
    full length, AA 1-155
    Origin
    • 9
    • 5
    Human
    Source
    • 9
    • 3
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This FIL1d protein is labelled with His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MVLSGALCFR MKDSALKVLY LHNNQLLAGG LHAGKVIKGE EISVVPNRWL DASLSPVILG VQGGSQCLSC GVGQEPTLTL EPVNIMELYL GAKESKSFTF YRRDMGLTSS FESAAYPGWF LCTVPEADQP VRLTQLPENG GWNAPITDFY FQQCD
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product FIL1d Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    FIL1d (Interleukin 1 delta (FIL1d))
    Alternative Name
    I36RA (FIL1d Products)
    Synonyms
    AI413231 Protein, Fil1delta Protein, IL36RN Protein, Il-1h3 Protein, Il1hy1 Protein, FIL1 Protein, FIL1(DELTA) Protein, FIL1D Protein, IL1F5 Protein, IL1HY1 Protein, IL1L1 Protein, IL1RP3 Protein, IL36RA Protein, PSORP Protein, Il1f5 Protein, interleukin 1 family, member 5 (delta) Protein, interleukin 36 receptor antagonist Protein, Il1f5 Protein, IL36RN Protein, Il36rn Protein
    Background
    Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling syst that is thought to be present in epithelial barriers and to take part in local inflammatory response, similar to the IL-1 syst with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.
    Molecular Weight
    32.95 kDa
    UniProt
    Q9UBH0
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