FIL1d Protein (AA 1-155, full length) (His-SUMO Tag)
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- Target See all FIL1d Proteins
- FIL1d (Interleukin 1 delta (FIL1d))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-155
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FIL1d protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MVLSGALCFR MKDSALKVLY LHNNQLLAGG LHAGKVIKGE EISVVPNRWL DASLSPVILG VQGGSQCLSC GVGQEPTLTL EPVNIMELYL GAKESKSFTF YRRDMGLTSS FESAAYPGWF LCTVPEADQP VRLTQLPENG GWNAPITDFY FQQCD
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product FIL1d Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- FIL1d (Interleukin 1 delta (FIL1d))
- Alternative Name
- I36RA (FIL1d Products)
- Synonyms
- AI413231 Protein, Fil1delta Protein, IL36RN Protein, Il-1h3 Protein, Il1hy1 Protein, FIL1 Protein, FIL1(DELTA) Protein, FIL1D Protein, IL1F5 Protein, IL1HY1 Protein, IL1L1 Protein, IL1RP3 Protein, IL36RA Protein, PSORP Protein, Il1f5 Protein, interleukin 1 family, member 5 (delta) Protein, interleukin 36 receptor antagonist Protein, Il1f5 Protein, IL36RN Protein, Il36rn Protein
- Background
- Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling syst that is thought to be present in epithelial barriers and to take part in local inflammatory response, similar to the IL-1 syst with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.
- Molecular Weight
- 32.95 kDa
- UniProt
- Q9UBH0
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