METTL11A Protein (AA 1-223, full length) (His-SUMO Tag)
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- Target See all METTL11A Proteins
- METTL11A (Methyltransferase Like 11A (METTL11A))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-223
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This METTL11A protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MTSEVIEDEK QFYSKAKTYW KQIPPTVDGM LGGYGHISSI DINSSRKFLQ RFLREGPNKT GTSCALDCGA GIGRITKRLL LPLFREVDMV DITEDFLVQA KTYLGEEGKR VRNYFCCGLQ DFTPEPDSYD VIWIQWVIGH LTDQHLAEFL RRCKGSLRPN GIIVIKDNMA QEGVILDDVD SSVCRDLDVV RRIICSAGLS LLAEERQENL PDEIYHVYSF ALR
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product METTL11A Protein
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Methyltransferase Like 11A (METTL11A) (AA 1-223) protein (His tag)
METTL11A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Methyltransferase Like 11A (METTL11A) (AA 1-223) protein (GST tag)METTL11A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Methyltransferase Like 11A (METTL11A) (AA 2-223) protein (His tag)Crystallography grade METTL11A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Methyltransferase Like 11A (METTL11A) (AA 1-223) protein (His tag)Crystallography grade METTL11A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Methyltransferase Like 11A (METTL11A) (AA 2-223) protein (His tag)Crystallography grade METTL11A Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Methyltransferase Like 11A (METTL11A) (AA 1-223) protein (His tag)Crystallography grade METTL11A Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Methyltransferase Like 11A (METTL11A) protein (Myc-DYKDDDDK Tag)METTL11A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- METTL11A (Methyltransferase Like 11A (METTL11A))
- Alternative Name
- NTM1A (METTL11A Products)
- Background
- Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.
- Molecular Weight
- 41.4 kDa
- UniProt
- Q9BV86
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