RABGEF1 Protein (AA 1-491, full length) (His-SUMO Tag)
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- Target See all RABGEF1 Proteins
- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-491
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RABGEF1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MSLKSERRGI HVDQSDLLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ IQEDWELAER LQREEEEAFA SSQSSQGAQS LTFSKFEEKK TNEKTRKVTT VKKFFSASSR VGSKKEIQEA KAPSPSINRQ TSIETDRVSK EFIEFLKTFH KTGQEIYKQT KLFLEGMHYK RDLSIEEQSE CAQDFYHNVA ERMQTRGKVP PERVEKIMDQ IEKYIMTRLY KYVFCPETTD DEKKDLAIQK RIRALRWVTP QMLCVPVNED IPEVSDMVVK AITDIIEMDS KRVPRDKLAC ITKCSKHIFN AIKITKNEPA SADDFLPTLI YIVLKGNPPR LQSNIQYITR FCNPSRLMTG EDGYYFTNLC CAVAFIEKLD AQSLNLSQED FDRYMSGQTS PRKQEAESWS PDACLGVKQM YKNLDLLSQL NERQERIMNE AKKLEKDLID WTDGIAREVQ DIVEKYPLEI KPPNQPLAAI DSENVENDKL PPPLQPQVYA G
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product RABGEF1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
- Alternative Name
- RABX5 (RABGEF1 Products)
- Synonyms
- Rab5ef Protein, Rabex5 Protein, Rin2 Protein, RABEX5 Protein, rabex-5 Protein, rabgef1 Protein, RAB guanine nucleotide exchange factor (GEF) 1 Protein, RAB guanine nucleotide exchange factor 1 Protein, RAB guanine nucleotide exchange factor (GEF) 1 L homeolog Protein, Rabgef1 Protein, RABGEF1 Protein, rabgef1.L Protein
- Background
- Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic mbrane fusion and mbrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase .
- Molecular Weight
- 72.85 kDa
- UniProt
- Q9UJ41
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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