GM2A Protein (AA 32-193) (GST tag)
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- Target See all GM2A Proteins
- GM2A (GM2 Ganglioside Activator (GM2A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-193
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GM2A protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- SSFSWDNCDE GKDPAVIRSL TLEPDPIIVP GNVTLSVMGS TSVPLSSPLK VDLVLEKEVA GLWIKIPCTD YIGSCTFEHF CDVLDMLIPT GEPCPEPLRT YGLPCHCPFK EGTYSLPKSE FVVPDLELPS WLTTGNYRIE SVLSSSGKRL GCIKIAASLK GI
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product GM2A Protein
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GM2 Ganglioside Activator (GM2A) (AA 26-193) protein (His tag)
GM2A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
GM2 Ganglioside Activator (GM2A) (AA 1-193) protein (GST tag)GM2A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
GM2 Ganglioside Activator (GM2A) (AA 94-193) protein (GST tag)GM2A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
GM2 Ganglioside Activator (GM2A) (AA 32-193) protein (His tag)Crystallography grade GM2A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
GM2 Ganglioside Activator (GM2A) (AA 34-193) protein (His tag)Crystallography grade GM2A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
GM2 Ganglioside Activator (GM2A) (AA 21-193) protein (His tag)Crystallography grade GM2A Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- GM2A (GM2 Ganglioside Activator (GM2A))
- Alternative Name
- SAP3 (GM2A Products)
- Synonyms
- GM2A Protein, fb96e04 Protein, fb96e10 Protein, wu:fb96e04 Protein, wu:fb96e10 Protein, zgc:110188 Protein, MGC84154 Protein, GM2-AP Protein, SAP-3 Protein, AA408702 Protein, AW215435 Protein, GM2 ganglioside activator Protein, GM2 ganglioside activator L homeolog Protein, GM2 ganglioside activator protein Protein, Gm2a Protein, GM2A Protein, gm2a Protein, gm2a.L Protein
- Background
- The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity . Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 Molecules from mbranes and presents th in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
- Molecular Weight
- 45 kDa
- UniProt
- P17900
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