RRAGA Protein (AA 1-247, partial) (GST tag)
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- Target See all RRAGA Proteins
- RRAGA (Ras-Related GTP Binding A (RRAGA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-247, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RRAGA protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MPNTAMKKKV LLMGKSGSGK TSMRSIIFAN YIARDTRRLG ATIDVEHSHV RFLGNLVLNL WDCGGQDTFM ENYFTSQRDN IFRNVEVLIY VFDVESRELE KDMHYYQSCL EAILQNSPDA KIFCLVHKMD LVQEDQRDLI FKEREEDLRR LSRPLECACF RTSIWDETLY KAWSSIVYQL IPNVQQLEMN LRNFAQIIEA DEVLLFERAT FLVISHYQCK EQRDVHRFEK ISNIIKQFKL SCSKLAA
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product RRAGA Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- RRAGA (Ras-Related GTP Binding A (RRAGA))
- Alternative Name
- RRAGA (RRAGA Products)
- Synonyms
- FIP-1 Protein, FIP1 Protein, RAGA Protein, 1300010C19Rik Protein, AI255374 Protein, Raga Protein, Ras related GTP binding A Protein, Ras-related GTP binding A Protein, RRAGA Protein, Rraga Protein
- Background
- Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.
- Molecular Weight
- 56.4 kDa
- UniProt
- Q7L523
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