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RRAGA Protein (AA 1-247, partial) (GST tag)

RRAGA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5712295
  • Target See all RRAGA Proteins
    RRAGA (Ras-Related GTP Binding A (RRAGA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-247, partial
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This RRAGA protein is labelled with GST tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MPNTAMKKKV LLMGKSGSGK TSMRSIIFAN YIARDTRRLG ATIDVEHSHV RFLGNLVLNL WDCGGQDTFM ENYFTSQRDN IFRNVEVLIY VFDVESRELE KDMHYYQSCL EAILQNSPDA KIFCLVHKMD LVQEDQRDLI FKEREEDLRR LSRPLECACF RTSIWDETLY KAWSSIVYQL IPNVQQLEMN LRNFAQIIEA DEVLLFERAT FLVISHYQCK EQRDVHRFEK ISNIIKQFKL SCSKLAA
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product RRAGA Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    RRAGA (Ras-Related GTP Binding A (RRAGA))
    Alternative Name
    RRAGA (RRAGA Products)
    Synonyms
    FIP-1 Protein, FIP1 Protein, RAGA Protein, 1300010C19Rik Protein, AI255374 Protein, Raga Protein, Ras related GTP binding A Protein, Ras-related GTP binding A Protein, RRAGA Protein, Rraga Protein
    Background
    Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.
    Molecular Weight
    56.4 kDa
    UniProt
    Q7L523
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