ANG Protein (AA 24-148) (His tag)
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- Target See all ANG Proteins
- ANG (Angiogenin (ANG))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-148
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Origin
- Cow
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ANG protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- AQDDYRYIHF LTQHYDAKPK GRNDEYCFNM MKNRRLTRPC KDRNTFIHGN KNDIKAICED RNGQPYRGDL RISKSEFQIT ICKHKGGSSR PPCRYGATED SRVIVVGCEN GLPVHFDESF ITPRH
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product ANG Protein
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Angiogenin (ANG) (AA 25-147) protein (His-IF2DI Tag)
ANG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Angiogenin (ANG) (AA 25-147) protein (GST tag)ANG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Angiogenin (ANG) (AA 25-147) protein (His tag)Crystallography grade ANG Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Angiogenin (ANG) (AA 25-145) protein (His tag)Crystallography grade ANG Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- ANG (Angiogenin (ANG))
- Alternative Name
- ANG1 (ANG Products)
- Synonyms
- ALS9 Protein, HEL168 Protein, RNASE4 Protein, RNASE5 Protein, ANG Protein, AI385586 Protein, Ang1 Protein, Rnase5 Protein, Rnase5a Protein, ANG1 Protein, angiogenin Protein, angiogenin, ribonuclease, RNase A family, 5 Protein, ribonuclease A family member k6 Protein, ANG Protein, Ang Protein, RNASE6 Protein
- Background
- Binds to actin on the surface of endothelial cells, once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assbly of stress granules (SGs) . Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo. Has very low ribonuclease activity.
- Molecular Weight
- 18.7 kDa
- UniProt
- P10152
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