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PRAME Protein (AA 1-509, full length) (His tag)

PRAME Origin: Human Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN5713748
  • Target See all PRAME Proteins
    PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
    Protein Type
    Recombinant
    Protein Characteristics
    full length, AA 1-509
    Origin
    Human
    Source
    • 5
    • 2
    • 1
    • 1
    Yeast
    Purification tag / Conjugate
    This PRAME protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MERRRLWGSI QSRYISMSVW TSPRRLVELA GQSLLKDEAL AIAALELLPR ELFPPLFMAA FDGRHSQTLK AMVQAWPFTC LPLGVLMKGQ HLHLETFKAV LDGLDVLLAQ EVRPRRWKLQ VLDLRKNSHQ DFWTVWSGNR ASLYSFPEPE AAQPMTKKRK VDGLSTEAEQ PFIPVEVLVD LFLKEGACDE LFSYLIEKVK RKKNVLRLCC KKLKIFAMPM QDIKMILKMV QLDSIEDLEV TCTWKLPTLA KFSPYLGQMI NLRRLLLSHI HASSYISPEK EEQYIAQFTS QFLSLQCLQA LYVDSLFFLR GRLDQLLRHV MNPLETLSIT NCRLSEGDVM HLSQSPSVSQ LSVLSLSGVM LTDVSPEPLQ ALLERASATL QDLVFDECGI TDDQLLALLP SLSHCSQLTT LSFYGNSISI SALQSLLQHL IGLSNLTHVL YPVPLESYED IHGTLHLERL AYLHARLREL LCELGRPSMV WLSANPCPHC GDRTFYDPEP ILCPCFMPN
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product PRAME Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
    Alternative Name
    PRAME (PRAME Products)
    Synonyms
    PRAME Protein, CT130 Protein, MAPE Protein, OIP-4 Protein, OIP4 Protein, 4930534P07Rik Protein, preferentially expressed antigen in melanoma Protein, PRAME Protein, Prame Protein
    Background
    Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
    Molecular Weight
    59.9 kDa
    UniProt
    P78395
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
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