UGT1A1 Protein (AA 26-533) (His tag)
-
- Target See all UGT1A1 Proteins
- UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-533
-
Origin
- Human
-
Source
- Yeast
- Purification tag / Conjugate
- This UGT1A1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- HAGKILLIPV DGSHWLSMLG AIQQLQQRGH EIVVLAPDAS LYIRDGAFYT LKTYPVPFQR EDVKESFVSL GHNVFENDSF LQRVIKTYKK IKKDSAMLLS GCSHLLHNKE LMASLAESSF DVMLTDPFLP CSPIVAQYLS LPTVFFLHAL PCSLEFEATQ CPNPFSYVPR PLSSHSDHMT FLQRVKNMLI AFSQNFLCDV VYSPYATLAS EFLQREVTVQ DLLSSASVWL FRSDFVKDYP RPIMPNMVFV GGINCLHQNP LSQEFEAYIN ASGEHGIVVF SLGSMVSEIP EKKAMAIADA LGKIPQTVLW RYTGTRPSNL ANNTILVKWL PQNDLLGHPM TRAFITHAGS HGVYESICNG VPMVMMPLFG DQMDNAKRME TKGAGVTLNV LEMTSEDLEN ALKAVINDKS YKENIMRLSS LHKDRPVEPL DLAVFWVEFV MRHKGAPHLR PAAHDLTWYQ YHSLDVIGFL LAVVLTVAFI TFKCCAYGYR KCLGKKGRVK KAHKSKTH
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product UGT1A1 Protein
-
UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 54-159) protein (GST tag)
UGT1A1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 26-533) protein (rho-1D4 tag)Crystallography grade UGT1A1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) protein (Myc-DYKDDDDK Tag)UGT1A1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Target
- UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
- Alternative Name
- UD11 (UGT1A1 Products)
- Synonyms
- BILIQTL1 Protein, GNT1 Protein, HUG-BR1 Protein, UDPGT Protein, UDPGT 1-1 Protein, UGT1 Protein, UGT1A Protein, Gnt1 Protein, UGT1A01 Protein, Udpgt-1a Protein, UgtBr1 Protein, Udpgt Protein, Ugt1 Protein, zgc:123097 Protein, UDP glucuronosyltransferase family 1 member A1 Protein, UDP glucuronosyltransferase 1 family, polypeptide A1 Protein, UDP-glucuronosyltransferase 1-1 Protein, UDP-glucuronosyltransferase Protein, UDP-glucuronosyltransferase 1-6 Protein, UDP glucuronosyltransferase 1 family polypeptide a1 Protein, UGT1A1 Protein, Ugt1a1 Protein, LOC100065342 Protein, LOC100125517 Protein, LOC100229734 Protein, LOC100405984 Protein, LOC100511479 Protein, ugt1a1 Protein
- Background
- UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.
- Molecular Weight
- 59.1 kDa
- UniProt
- P22309
- Pathways
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
-
