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HES2 Protein (AA 1-173) (His tag)

HES2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % by SDS - PAGE SDS
Catalog No. ABIN5778575
  • Target See all HES2 Proteins
    HES2 (Hairy and Enhancer of Split 2 (HES2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-173
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HES2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSMGLPRRA GDAAELRKSL KPLLEKRRRA RINQSLSQLK GLILPLLGRE NSNCSKLEKA DVLEMTVRFL QELPASSWPT AAPLPCDSYR EGYSACVARL ARVLPACRVL EPAVSARLLE HLWRRAASAT LDGGRAGDSS GPSAPAPAPA SAPEPASAPV PSPPSPPCGP GLWRPW
    Purity
    > 80 % by SDS - PAGE
    Top Product
    Discover our top product HES2 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Denatured

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    HES2 (Hairy and Enhancer of Split 2 (HES2))
    Alternative Name
    HES2 (HES2 Products)
    Synonyms
    HES2 Protein, bHLHb40 Protein, HES-2 Protein, hes family bHLH transcription factor 2 Protein, hairy and enhancer of split 2 (Drosophila) Protein, HES2 Protein, Hes2 Protein
    Background
    Hairy and enhancer of split 2, also known as HES2, is a member of the HES family and contains one basic helix-loop-helix (bHLH) domain and one orange domain. The HES family members form a complex with TLE, the mammalian homologue of Groucho, and this interaction is mediated by the carboxy terminal WRPW motif of the HES proteins. Activation of Notch signaling pathway leads to activation of HES family genes through the interaction between Notch intracellular domain and RBPSuH (CSL). HES2 is expressed in a variety of adult and embryonic tissue. Recombinant human HES2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Molecular Weight
    20.9 kDa (196aa)
    NCBI Accession
    NP_061962
    UniProt
    Q9Y543
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