PNRC2 Protein (AA 1-139) (His tag)
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- Target See all PNRC2 Proteins
- PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-139
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PNRC2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMGGGERY NIPAPQSRNV SKNQQQLNRQ KTKEQNSQMK IVHKKKERGH GYNSSAAAWQ AMQNGGKNKN FPNNQSWNSS LSGPRLLFKS QANQNYAGAK FSEPPSPSVL PKPPSHWVPV SFNPSDKEIM TFQLKTLLKV QV
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PNRC2 Protein
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Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (AA 1-140) protein (Strep Tag)
Crystallography grade PNRC2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (AA 1-139) protein (Strep Tag)Crystallography grade PNRC2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (AA 1-139) protein (His tag)PNRC2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))
- Alternative Name
- PNRC2 (PNRC2 Products)
- Synonyms
- 0610011E17Rik Protein, D4Bwg0593e Protein, wu:cegs2777 Protein, wu:fb51a04 Protein, wu:fb81a06 Protein, wu:fd19g06 Protein, proline rich nuclear receptor coactivator 2 Protein, proline-rich nuclear receptor coactivator 2 Protein, PNRC2 Protein, Pnrc2 Protein, pnrc2 Protein
- Background
- PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. This protein may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. It is required for uPF1/RENT1 localization to the P-body and also acts as a nuclear receptor coactivator. PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure. Recombinant human PNCR2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 18.0kDa (162aa)
- NCBI Accession
- NP_060231
- UniProt
- Q9NPJ4
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