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COPE Protein (AA 1-308) (His tag)

COPE Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN5779054
  • Target See all COPE Proteins
    COPE (Coatomer Protein Complex, Subunit epsilon (COPE))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-308
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This COPE protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSMAPPAPG PASGGSGEVD ELFDVKNAFY IGSYQQCINE AQRVKLSSPE RDVERDVFLY RAYLAQRKFG VVLDEIKPSS APELQAVRMF ADYLAHESRR DSIVAELDRE MSRSVDVTNT TFLLMAASIY LHDQNPDAAL RALHQGDSLE CTAMTVQILL KLDRLDLARK ELKRMQDLDE DATLTQLATA WVSLATGGEK LQDAYYIFQE MADKCSPTLL LLNGQAACHM AQGRWEAAEG LLQEALDKDS GYPETLVNLI VLSQHLGKPP EVTNRYLSQL KDAHRSHPFI KEYQAKENDF DRLVLQYAPS A
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product COPE Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid, In Phosphate buffered saline (  pH 7.4) containing 20 % glycerol, 1  mM DTT
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    COPE (Coatomer Protein Complex, Subunit epsilon (COPE))
    Alternative Name
    COPE (COPE Products)
    Synonyms
    COPE Protein, DDBDRAFT_0189670 Protein, DDBDRAFT_0233799 Protein, DDB_0189670 Protein, DDB_0233799 Protein, DKFZp469K1716 Protein, MGC80063 Protein, MGC130714 Protein, epsilon-COP Protein, 1110005D17Rik Protein, Cope1 Protein, coatomer protein complex subunit epsilon Protein, coatomer protein complex epsilon subunit Protein, coatomer protein complex subunit epsilon S homeolog Protein, coatomer protein complex, subunit epsilon Protein, COPE Protein, copE Protein, cope.S Protein, cope Protein, Cope Protein
    Background
    COPE is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. Recombinant human COPE protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    36.9 kDa (331aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_009194
    UniProt
    O14579
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