ISCU Protein (AA 35-167) (His tag)
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- Target See all ISCU Proteins
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 35-167
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ISCU protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- ISCU, 35-167aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ISCU Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 100mM NaCl
- Storage
- 4 °C
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- Target
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
- Alternative Name
- ISCU (ISCU Products)
- Synonyms
- nifun Protein, zC191D15.3 Protein, si:ch211-191d15.3 Protein, 2310020H20Rik Protein, HML Protein, ISU2 Protein, NIFU Protein, NIFUN Protein, hnifU Protein, RGD1309562 Protein, AA407971 Protein, Nifu Protein, Nifun Protein, iron-sulfur cluster assembly enzyme ISCU, mitochondrial Protein, iron-sulfur cluster assembly enzyme Protein, iron-sulfur cluster assembly enzyme a Protein, LOC409130 Protein, ISCU Protein, iscua Protein, Iscu Protein
- Background
- Iron-sulfur cluster assembly enzyme, also known as ISCU, is a member of the nifU family. Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. It is interact with ISCS, a cysteine desulfurase, to sequester inorganic sulfur for Fe-S cluster assembly. ISCU-ISCS protein complex localizes in both mitochondria and cytosol, implying that Fe-S cluster assembly takes place in multiple subcellular compartments in mammalian cells. Recombinant human ISCU protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Iron-sulfur cluster assembly enzyme ISCU, HML, hnifU, ISU2, NIFU, NIFUN. NCBI no.: NP_998760
- Molecular Weight
- 16.7kDa (154aa), confirmed by MALDI-TOF
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