KRT8 Protein (AA 1-483) (His tag)
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- Target See all KRT8 Proteins
- KRT8 (Keratin 8 (KRT8))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-483
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This KRT8 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMSIRVTQ KSYKVSTSGP RAFSSRSYTS GPGSRISSSS FSRVGSSNFR GGLGGGYGGA SGMGGITAVT VNQSLLSPLV LEVDPNIQAV RTQEKEQIKT LNNKFASFID KVRFLEQQNK MLETKWSLLQ QQKTARSNMD NMFESYINNL RRQLETLGQE KLKLEAELGN MQGLVEDFKN KYEDEINKRT EMENEFVLIK KDVDEAYMNK VELESRLEGL TDEINFLRQL YEEEIRELQS QISDTSVVLS MDNSRSLDMD SIIAEVKAQY EDIANRSRAE AESMYQIKYE ELQSLAGKHG DDLRRTKTEI SEMNRNISRL QAEIEGLKGQ RASLEAAIAD AEQRGELAIK DANAKLSELE AALQRAKQDM ARQLREYQEL MNVKLALDIE IATYRKLLEG EESRLESGMQ NMSIHTKTTS GYAGGLSSAY GGLTSPGLSY SLGSSFGSGA GSSSFSRTSS SRAVVVKKIE TRDGKLVSES SDVLPK
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product KRT8 Protein
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Keratin 8 (KRT8) (AA 1-483) protein (GST tag)
KRT8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Keratin 8 (KRT8) (AA 91-195) protein (GST tag)KRT8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Keratin 8 (KRT8) (AA 1-483) protein (His tag)KRT8 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Keratin 8 (KRT8) (AA 1-490) protein (Strep Tag)Crystallography grade KRT8 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Keratin 8 (KRT8) (AA 2-483), (full length) protein (GST tag)KRT8 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
Keratin 8 (KRT8) (AA 2-483), (full length) protein (His-SUMO Tag)KRT8 Origin: Human Host: Escherichia coli (E. coli) Recombinant ELISA
Keratin 8 (KRT8) protein (Myc-DYKDDDDK Tag)KRT8 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- KRT8 (Keratin 8 (KRT8))
- Alternative Name
- KRT8 (KRT8 Products)
- Synonyms
- CARD2 Protein, CK-8 Protein, CK8 Protein, CYK8 Protein, K2C8 Protein, K8 Protein, KO Protein, AA960620 Protein, AL022697 Protein, AU019895 Protein, Card2 Protein, EndoA Protein, Krt-2.8 Protein, Krt2-8 Protein, CYKER Protein, KRT2-8 Protein, KERATIN8 Protein, ck8 Protein, cyk8 Protein, k2c8 Protein, card2 Protein, krt2-5 Protein, MGC69490 Protein, KRT8 Protein, DreK8 Protein, cb186 Protein, krt2-8 Protein, sb:cb186 Protein, wu:fa20h05 Protein, wu:fa95h10 Protein, wu:fb96c06 Protein, zf-K8 Protein, zfk8 Protein, DKFZp468F2127 Protein, keratin 8 Protein, keratin 8 S homeolog Protein, KRT8 Protein, Krt8 Protein, krt8.S Protein, krt8 Protein
- Background
- KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Recombinant human KRT8 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 56 kDa (506aa)
- NCBI Accession
- NP_002264
- UniProt
- P05787
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