TOMM20 Protein (AA 25-145) (His tag)

Catalog No. ABIN5852987

Product Details

Target: TOMM20 (Mitochondrial Import Receptor Subunit TOM20 homolog (TOMM20))

Protein Type: Recombinant

Protein Characteristics: AA 25-145

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This TOMM20 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSDRKRRSD PNFKNRLRER RKKQKLAKER AGLSKLPDLK DAEAVQKFFL EEIQLGEELL AQGEYEKGVD HLTNAIAVCG QPQQLLQVLQ QTLPPPVFQM LLTKLPTISQ RIVSAQSLAE DDVE

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.1M NaCl, 20 % glycerol, 2  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: TOMM20 (Mitochondrial Import Receptor Subunit TOM20 homolog (TOMM20))

Alternative Name: TOMM20 (TOMM20 Products)

Synonyms: MAS20 Protein, MOM19 Protein, TOM20 Protein, 1810060K07Rik Protein, BB284719 Protein, Gm19268 Protein, mKIAA0016 Protein, tomm20 Protein, wu:fk47b11 Protein, zgc:73165 Protein, mas20 Protein, mom19 Protein, tom20 Protein, zgc:92628 Protein, translocase of outer mitochondrial membrane 20 Protein, translocase of outer mitochondrial membrane 20 homolog (yeast) Protein, Mitochondrial import receptor subunit TOM20 homolog Protein, translocase of outer mitochondrial membrane 20 homolog L homeolog Protein, translocase of outer mitochondrial membrane 20b Protein, TOMM20 Protein, Tomm20 Protein, tomm20a Protein, tomm-20 Protein, tomm20.L Protein, tomm20b Protein

Background: Mmitochondrial import receptor subunit TOMM20 homolog, also known as TOMM20, belongs to the Tom20 family. The Tom machinery consists of import receptors for the initial binding of cytosolically synthesized preproteins and a general import pore (GIP) for the membrane translocation of various preproteins into the mitochondria. TOMM20 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. Recombinant human TOMM20 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 16.2kDa (144aa), confirmed by MALDI-TOF

NCBI Accession: NP_055580

UniProt: Q15388

Pathways: Unfolded Protein Response