HLA-DOA Protein (AA 26-217) (His tag)
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- Target See all HLA-DOA Proteins
- HLA-DOA (HLA Class II DO alpha (HLA-DOA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-217
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HLA-DOA protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSTKADHMG SYGPAFYQSY GASGQFTHEF DEEQLFSVDL KKSEAVWRLP EFGDFARFDP QGGLAGIAAI KAHLDILVER SNRSRAINVP PRVTVLPKSR VELGQPNILI CIVDNIFPPV INITWLRNGQ TVTEGVAQTS FYSQPDHLFR KFHYLPFVPS AEDVYDCQVE HWGLDAPLLR HWELQVPIPP PDAME
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product HLA-DOA Protein
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HLA Class II DO alpha (HLA-DOA) (AA 28-125) protein (GST tag)
HLA-DOA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
HLA Class II DO alpha (HLA-DOA) (AA 26-217) protein (His tag)Crystallography grade HLA-DOA Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
HLA Class II DO alpha (HLA-DOA) (AA 26-250) protein (rho-1D4 tag)Crystallography grade HLA-DOA Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- HLA-DOA (HLA Class II DO alpha (HLA-DOA))
- Alternative Name
- HLA-DOA (HLA-DOA Products)
- Synonyms
- HLA-DNA Protein, HLA-DZA Protein, HLADZ Protein, major histocompatibility complex, class II, DO alpha Protein, HLA-DOA Protein
- Background
- HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. Recombinant human HLA-DAO protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 24.1 kDa (215aa)
- NCBI Accession
- NP_002110
- UniProt
- P06340
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