PEX26 Protein (AA 1-246) (His tag)
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- Target See all PEX26 Proteins
- PEX26 (Peroxisomal Biogenesis Factor 26 (PEX26))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-246
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PEX26 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMKSDSST SAAPLRGLGG PLRSSEPVRA VPARAPAVDL LEEAADLLVV HLDFRAALET CERAWQSLAN HAVAEEPAGT SLEVKCSLCV VGIQALAEMD RWQEVLSWVL QYYQVPEKLP PKVLELCILL YSKMQEPGAV LDVVGAWLQD PANQNLPEYG ALAEFHVQRV LLPLGCLSEA EELVVGSAAF GEERRLDVLQ AIHTARQQQK QEHSGSEEAQ KPNLEGSVSH KFLSLPMLVR QLWDSAVSH
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PEX26 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- PEX26 (Peroxisomal Biogenesis Factor 26 (PEX26))
- Alternative Name
- PEX26 (PEX26 Products)
- Synonyms
- fk41g06 Protein, zgc:64014 Protein, wu:fk41g06 Protein, PBD7A Protein, PBD7B Protein, PEX26M1T Protein, Pex26pM1T Protein, 4632428M11Rik Protein, AI853212 Protein, peroxisomal biogenesis factor 26 Protein, peroxisomal biogenesis factor 26 L homeolog Protein, pex26 Protein, PEX26 Protein, pex26.L Protein, Pex26 Protein
- Background
- PEX26 belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Alternatively spliced transcript variants have been identified for this gene. Recombinant human PEX26 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 29.3 kDa (269aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_001121121
- UniProt
- Q7Z412
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