NAP1L4 Protein (AA 1-375) (His tag)

Catalog No. ABIN5853226

Product Details

Target: NAP1L4 (Nucleosome Assembly Protein 1-Like 4 (NAP1L4))

Protein Type: Recombinant

Protein Characteristics: AA 1-375

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NAP1L4 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMADHSFS DGVPSDSVEA AKNASNTEKL TDQVMQNPRV LAALQERLDN VPHTPSSYIE TLPKAVKRRI NALKQLQVRC AHIEAKFYEE VHDLERKYAA LYQPLFDKRR EFITGDVEPT DAESEWHSEN EEEEKLAGDM KSKVVVTEKA AATAEEPDPK GIPEFWFTIF RNVDMLSELV QEYDEPILKH LQDIKVKFSD PGQPMSFVLE FHFEPNDYFT NSVLTKTYKM KSEPDKADPF SFEGPEIVDC DGCTIDWKKG KNVTVKTIKK KQKHKGRGTV RTITKQVPNE SFFNFFNPLK ASGDGESLDE DSEFTLASDF EIGHFFRERI VPRAVLYFTG EAIEDDDNFE EGEEGEEEEL EGDEEGEDED DAEINPKV

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: NAP1L4 (Nucleosome Assembly Protein 1-Like 4 (NAP1L4))

Alternative Name: NAP1L4 (NAP1L4 Products)

Synonyms: B-TG1 Protein, Beta-TG Protein, CTAP-III Protein, CTAP3 Protein, CTAPIII Protein, CXCL7 Protein, LA-PF4 Protein, LDGF Protein, MDGF Protein, NAP-2 Protein, PBP Protein, SCYB7 Protein, TC1 Protein, TC2 Protein, TGB Protein, TGB1 Protein, THBGB Protein, THBGB1 Protein, NAP1L4b Protein, NAP2 Protein, NAP2L Protein, hNAP2 Protein, cb910 Protein, nap1l4 Protein, wu:fa99c07 Protein, NAP1L4 Protein, DKFZp468A247 Protein, 2810410H14Rik Protein, AI316776 Protein, D7Wsu30e Protein, Nap2 Protein, zgc:101613 Protein, pro-platelet basic protein Protein, nucleosome assembly protein 1 like 4 Protein, nucleosome assembly protein 1-like 4a Protein, nucleosome assembly protein 1-like 4 Protein, nucleosome assembly protein Nap1 Protein, nucleosome assembly protein 1-like 4b Protein, PPBP Protein, NAP1L4 Protein, nap1l4a Protein, Nap1l4 Protein, SJAG_02314 Protein, nap1l4b Protein

Background: NAP1L4 is a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Recombinant human NAP1L4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 45.2 kDa (398aa), confirmed by MALDI-TOF

NCBI Accession: NP_005960

UniProt: Q99733