ACOT11 Protein (AA 19-250) (His tag)
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- Target See all ACOT11 Proteins
- ACOT11 (Acyl-CoA Thioesterase 11 (ACOT11))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-250
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ACOT11 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSNRTS RKSALRAGND SAMADGEGYR NPTEVQMSQL VLPCHTNQRG ELSVGQLLKW IDTTACLSAE RHAGCPCVTA SMDDIYFEHT ISVGQVVNIK AKVNRAFNSS MEVGIQVASE DLCSEKQWNV CKALATFVAR REITKVKLKQ ITPRTEEEKM EHSVAAERRR MRLVYADTIK DLLANCAIQG DLESRDCSRM VPAEKTRVES VELVLPPHAN HQGNTFGGQI MAWMENVA
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ACOT11 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- ACOT11 (Acyl-CoA Thioesterase 11 (ACOT11))
- Alternative Name
- BFIT (ACOT11 Products)
- Synonyms
- BFIT Protein, STARD14 Protein, THEA Protein, THEM1 Protein, 1110020M10Rik Protein, 2010309H15Rik Protein, AW060409 Protein, BFIT1 Protein, Thea Protein, Them1 Protein, mKIAA0707 Protein, acot11 Protein, zgc:113011 Protein, ACOT11 Protein, DKFZp469E1816 Protein, acyl-CoA thioesterase 11 Protein, acyl-CoA thioesterase 11a Protein, acyl-CoA thioesterase 11 L homeolog Protein, ACOT11 Protein, Acot11 Protein, acot11a Protein, acot11.L Protein, acot11 Protein
- Background
- BFIT is a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. The protein has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Recombinant human BFIT protein, fused to His-tag at N-terminus, was expressed in E.coli
- Molecular Weight
- 29.9kDa (268aa)
- NCBI Accession
- NP_671517
- UniProt
- Q8WXI4
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