Dynamitin Protein (AA 1-403) (His tag)
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- Target See all Dynamitin (DCTN2) Proteins
- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-403
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Dynamitin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMADPKYA DLPGIARNEP DVYETSDLPE DDQAEFDAEL EELTSTSVEH IIVNPNAAYD KFKDKRVGTK GLDFSDRIGK TKRTGYESGE YEMLGEGLGV KETPQQKYQR LLHEVQELTT EVEKIKTTVK ESATEEKLTP VLLAKQLAAL KQQLVASHLE KLLGPDAAIN LTDPDGALAK RLLLQLEATK NSKGGSGGKT TGTPPDSSLV TYELHSRPEQ DKFSQAAKVA ELEKRLTELE TAVRCDQDAQ NPLSAGLQGA CLMETVELLQ AKVSALDLAV LDQVEARLQS VLGKVNEIAK HKASVEDADT QSKVHQLYET IQRWSPIAST LPELVQRLVT IKQLHEQAMQ FGQLLTHLDT TQQMIANSLK DNTTLLTQVQ TTMRENLATV EGNFASIDER MKKLGK
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product DCTN2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
- Alternative Name
- DCTN2 (DCTN2 Products)
- Synonyms
- DCTN2 Protein, dctn2 Protein, dctn50 Protein, dynamitin Protein, rbp50 Protein, CG8269 Protein, DMN Protein, Dmel\\CG8269 Protein, P50 Protein, dDyn Protein, dmn Protein, dyna Protein, l(2)k16109 Protein, l(2)k16218 Protein, p50 Protein, p50/Dmn Protein, p50/dynamitin Protein, 2310042E05Rik Protein, C130077D06Rik Protein, C87049 Protein, DCTN-50 Protein, GMP23-48K Protein, RBP50 Protein, DCTN50 Protein, DYNAMITIN Protein, zgc:63867 Protein, dynactin subunit 2 Protein, dynactin subunit 2 S homeolog Protein, Dynactin 2, p50 subunit Protein, dynactin 2 Protein, dynactin 2 (p50) Protein, dynactin subunit 2 L homeolog Protein, DCTN2 Protein, dctn2.S Protein, DCTN2-p50 Protein, dctn2 Protein, Dctn2 Protein, dctn2.L Protein
- Background
- Dynactin 2, also known as DCTN2, modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. This protein is involved in anchoring microtubules to centrosomes. This protein may play a role in synapse formation during brain development. Recombinant human DCTN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 46.9kDa (426aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_001248341
- UniProt
- Q13561
- Pathways
- M Phase, Ribonucleoprotein Complex Subunit Organization
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