TIMM8A/DDP Protein (AA 1-97) (His tag)
TIMM8A
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS - PAGE
SDS
1 image
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- Target See all TIMM8A/DDP (TIMM8A) Proteins
- TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-97
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TIMM8A/DDP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMDSSSSS SAAGLGAVDP QLQHFIEVET QKQRFQQLVH QMTELCWEKC MDKPGPKLDS RAEACFVNCV ERFIDTSQFI LNRLEQTQKS KPVFSESLSD
- Purity
- > 90 % by SDS - PAGE
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Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 1-72) protein (GST tag)
TIMM8A Origin: Human Host: Wheat germ Recombinant ELISA, AP, AA, WB
Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TIMM8A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 30 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
- Alternative Name
- TIMM8A (TIMM8A Products)
- Background
- TIMM8A is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome, an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Recombinant human TIMM8A proten, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 13.4kDa (120aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_004076
- UniProt
- O60220
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