MX2 Protein (AA 626-715) (His tag)
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- Target See all MX2 Proteins
- MX2 (MX dynamin like GTPase 2 (MX2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 626-715
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MX2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSIGIH LNAYFLETSK RLANQIPFII QYFMLRENGD SLQKAMMQIL QEKNRYSWLL QEQSETATKR RILKERIYRL TQARHALCQF SSKEIH
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product MX2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- MX2 (MX dynamin like GTPase 2 (MX2))
- Alternative Name
- MX2 (MX2 Products)
- Synonyms
- AI528743 Protein, Mx-2 Protein, Mx3 Protein, MXB Protein, MX dynamin-like GTPase 2 Protein, MX dynamin like GTPase 2 Protein, myxovirus (influenza virus) resistance 2 (mouse) Protein, Mx2 Protein, MX2 Protein
- Background
- MX2 has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. Recombinant human MX2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 14.9 kDa (126aa)
- NCBI Accession
- NP_002454
- UniProt
- P20592
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