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MX2 Protein (AA 626-715) (His tag)

MX2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN5853486
  • Target See all MX2 Proteins
    MX2 (MX dynamin like GTPase 2 (MX2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 626-715
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This MX2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSIGIH LNAYFLETSK RLANQIPFII QYFMLRENGD SLQKAMMQIL QEKNRYSWLL QEQSETATKR RILKERIYRL TQARHALCQF SSKEIH
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product MX2 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Denatured

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    MX2 (MX dynamin like GTPase 2 (MX2))
    Alternative Name
    MX2 (MX2 Products)
    Synonyms
    AI528743 Protein, Mx-2 Protein, Mx3 Protein, MXB Protein, MX dynamin-like GTPase 2 Protein, MX dynamin like GTPase 2 Protein, myxovirus (influenza virus) resistance 2 (mouse) Protein, Mx2 Protein, MX2 Protein
    Background
    MX2 has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. Recombinant human MX2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Molecular Weight
    14.9 kDa (126aa)
    NCBI Accession
    NP_002454
    UniProt
    P20592
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