RAMP1 Protein (AA 27-117) (His tag)
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- Target See all RAMP1 Proteins
- RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-117
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RAMP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSCQEANYG ALLRELCLTQ FQVDMEAVGE TLWCDWGRTI RSYRELADCT WHMAEKLGCF WPNAEVDRFF LAVHGRYFRS CPISGRAVRD PPGS
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product RAMP1 Protein
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Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1) (AA 1-148) protein (GST tag)
RAMP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1) (AA 27-117) protein (GST tag)RAMP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1) (AA 27-148) protein (rho-1D4 tag)Crystallography grade RAMP1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1) (AA 27-148) protein (rho-1D4 tag)Crystallography grade RAMP1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))
- Alternative Name
- RAMP1 (RAMP1 Products)
- Background
- RAMP is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Recombinant human RAMP1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 12.9 kDa (114aa)
- NCBI Accession
- NP_005846
- UniProt
- O60894
- Pathways
- cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
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