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LECT1 Protein (AA 214-333) (His tag)

LECT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN5853515
  • Target See all LECT1 Proteins
    LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 214-333
    Origin
    • 6
    • 4
    Human
    Source
    • 4
    • 4
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This LECT1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSREVVRKI VPTTTKRPHS GPRSNPGAGR LNNETRPSVQ EDSQAFNPDN PYHQEGESMT FDPRLDHEGI CCIECRRSYT HCQKICEPLG GYYPWPYNYQ GCRSACRVIM PCSWWVARIL GMV
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product LECT1 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Denatured

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M uREA, 10 % glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))
    Alternative Name
    LECT1 (LECT1 Products)
    Synonyms
    chm1 Protein, chm-i Protein, bricd3 Protein, MGC53801 Protein, MGC82444 Protein, chondromodulin-I Protein, Lect1 Protein, BRICD3 Protein, CHM-I Protein, CHM1 Protein, MYETS1 Protein, Bricd3 Protein, ChM-I Protein, Chm-1 Protein, chondromodulin L homeolog Protein, leukocyte cell derived chemotaxin 1 Protein, chondromodulin Protein, cnmd.L Protein, lect1 Protein, CNMD Protein, cnmd Protein, Cnmd Protein
    Background
    LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. Recombinant human LECT1 protein, fused to His-tag at N-terminus, was expressed in E.coli
    Molecular Weight
    16.2kDa (143aa)
    NCBI Accession
    NP_001011705
    UniProt
    O75829
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