BCAR1 Protein (AA 465-848) (His tag)
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- Target See all BCAR1 Proteins
- BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 465-848
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BCAR1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSRLQQGVS ATVAHLLDLA GSAGATGSWR SPSEPQEPLV QDLQAAVAAV QSAVHELLEF ARSAVGNAAH TSDRALHAKL SRQLQKMEDV HQTLVAHGQA LDAGRGGSGA TLEDLDRLVA CSRAVPEDAK QLASFLHGNA SLLFRRTKAT APGPEGGGTL HPNPTDKTSS IQSRPLPSPP KFTSQDSPDG QYENSEGGWM EDYDYVHLQG KEEFEKTQKE LLEKGSITRQ GKSQLELQQL KQFERLEQEV SRPIDHDLAN WTPAQPLAPG RTGGLGPSDR QLLLFYLEQC EANLTTLTNA VDAFFTAVAT NQPPKIFVAH SKFVILSAHK LVFIGDTLSR QAKAADVRSQ VTHYSNLLCD LLRGIVATTK AAALQYPSPS AAQDMVE
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product BCAR1 Protein
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Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (AA 413-698) protein (His tag)
BCAR1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (AA 1-870) protein (GST tag)BCAR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (AA 771-870) protein (GST tag)BCAR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (AA 1-870) protein (Strep Tag)Crystallography grade BCAR1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (AA 1-874) protein (Strep Tag)Crystallography grade BCAR1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) protein (Myc-DYKDDDDK Tag)BCAR1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))
- Alternative Name
- BCAR1 (BCAR1 Products)
- Synonyms
- CAS Protein, CAS1 Protein, CASS1 Protein, CRKAS Protein, P130Cas Protein, AI385681 Protein, Cas Protein, Crkas Protein, P130CAS Protein, MGC68466 Protein, cas Protein, p130cas Protein, BCAR1 Protein, fc17f11 Protein, wu:fc17f11 Protein, zgc:175192 Protein, BCAR1, Cas family scaffolding protein Protein, breast cancer anti-estrogen resistance 1 Protein, breast cancer anti-estrogen resistance 1 L homeolog Protein, breast cancer anti-estrogen resistance protein 1 Protein, BCAR1 Protein, Bcar1 Protein, bcar1.L Protein, bcar1 Protein, LOC100435586 Protein
- Background
- BCAR1, or CAS, is an Src family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion. Recombinant human BCAR1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 43.9kDa (407aa)
- NCBI Accession
- NP_055382
- UniProt
- P56945
- Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
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