APOC1 Protein (AA 27-83) (His tag)
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- Target See all APOC1 Proteins
- APOC1 (Apolipoprotein C-I (APOC1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-83
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This APOC1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSTPDVSSA LDKLKEFGNT LEDKARELIS RIKQSELSAK MREWFSETFQ KVKEKLKIDS
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product APOC1 Protein
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Apolipoprotein C-I (APOC1) (AA 27-83) protein (His tag)
APOC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Apolipoprotein C-I (APOC1) (AA 1-83) protein (GST tag)APOC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Apolipoprotein C-I (APOC1) (AA 29-83) protein (His tag)Crystallography grade APOC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Apolipoprotein C-I (APOC1) (AA 29-88) protein (His tag)Crystallography grade APOC1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Apolipoprotein C-I (APOC1) (AA 27-88) protein (His tag)Crystallography grade APOC1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- APOC1 (Apolipoprotein C-I (APOC1))
- Alternative Name
- APOC1 (APOC1 Products)
- Synonyms
- Apo-CIB Protein, ApoC-IB Protein, ALPCI Protein, LRRG04 Protein, APOC1 Protein, apoc1 Protein, apolipoprotein C1 Protein, apolipoprotein C-I Protein, Apolipoprotein C-I Protein, APOC1 Protein, Apoc1 Protein, apoc1 Protein
- Background
- APOC1 is a member of the apolipoprotein C family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. It is mapped to chromosome 19, where it resides within an apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. APOC1 has a length of 57 amino acids normally found in plasma and responsible for the activation of esterified lechitin cholesterol with an important role in the exchange of esterified cholesterol between lipoproteins and in removal of cholesterol from tissues. Its main function is inhibition of CETP, probably by altering the electric charge of HDL molecules. Recombinant human APOC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 9 kDa (80aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_001636
- UniProt
- P02654
- Pathways
- Apoptosis
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