SERPINC1 Protein (AA 33-464) (His tag)
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- Target See all SERPINC1 Proteins
- SERPINC1 (Serpin Family C Member 1 (SERPINC1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 33-464
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SERPINC1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSHGSPVDI CTAKPRDIPM NPMCIYRSPE KKATEDEGSE QKIPEATNRR VWELSKANSR FATTFYQHLA DSKNDNDNIF LSPLSISTAF AMTKLGACND TLQQLMEVFK FDTISEKTSD QIHFFFAKLN CRLYRKANKS SKLVSANRLF GDKSLTFNET YQDISELVYG AKLQPLDFKE NAEQSRAAIN KWVSNKTEGR ITDVIPSEAI NELTVLVLVN TIYFKGLWKS KFSPENTRKE LFYKADGESC SASMMYQEGK FRYRRVAEGT QVLELPFKGD DITMVLILPK PEKSLAKVEK ELTPEVLQEW LDELEEMMLV VHMPRFRIED GFSLKEQLQD MGLVDLFSPE KSKLPGIVAE GRDDLYVSDA FHKAFLEVNE EGSEAAASTA VVIAGRSLNP NRVTFKANRP FLVFIREVPL NTIIFMGRVA NPCVK
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product SERPINC1 Protein
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Serpin Family C Member 1 (SERPINC1) (AA 1-259) protein (GST tag)
SERPINC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Serpin Family C Member 1 (SERPINC1) (AA 33-464) protein (His tag)Crystallography grade SERPINC1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Serpin Family C Member 1 (SERPINC1) (AA 33-465) protein (His tag)Crystallography grade SERPINC1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- SERPINC1 (Serpin Family C Member 1 (SERPINC1))
- Alternative Name
- SERPINC1 (SERPINC1 Products)
- Synonyms
- AT3 Protein, AT3D Protein, ATIII Protein, THPH7 Protein, SERPINC1 Protein, DKFZp470C1733 Protein, AI114908 Protein, At-3 Protein, At3 Protein, ANTITHROMBIN, AT-III Protein, AT-III Protein, serpin family C member 1 Protein, antithrombin-III Protein, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 Protein, SERPINC1 Protein, CpipJ_CPIJ000472 Protein, CpipJ_CPIJ013111 Protein, Serpinc1 Protein
- Background
- Antithrombin-III precursor, also known as SERPINC1, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The inhibitory activity of SERPINC1 is amplified in the presence of heparin. SERPINC1 inhibits Thrombin and Factors IXa, Xa and XIa. Defects in the gene SERPINC1, which encodes for ATIII, can cause ATIII deficiency, an autosomal dominant disease which is a risk factor for hereditary thrombophilia. Recombinant human SERPINC1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 51.4kDa (455aa)
- NCBI Accession
- NP_000479
- UniProt
- P01008
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