TGFBRAP1 Protein (AA 601-860) (His tag)
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- Target See all TGFBRAP1 Proteins
- TGFBRAP1 (Transforming Growth Factor, beta Receptor Associated Protein 1 (TGFBRAP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 601-860
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TGFBRAP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSKRLQ KEEYHTHLAV LYLEEVLLQR ASASGKGAEA TETQAKLRRL LQKSDLYRVH FLLERLQGAG LPMESAILHG KLGEHEKALH ILVHELQDFA AAEDYCLWCS EGRDPPHRQQ LFHTLLAIYL HAGPTAHELA VAAVDLLNRH ATEFDAAQVL QMLPDTWSVQ LLCPFLMGAM RDSIHARRTM QVALGLARSE NLIYTYDKMK LKGSSIQLSD KKLCQICQNP FCEPVFVRYP NGGLVHTHCA ASRHTNPSSS SPGTRT
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product TGFBRAP1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- TGFBRAP1 (Transforming Growth Factor, beta Receptor Associated Protein 1 (TGFBRAP1))
- Alternative Name
- TGFBRAP1 (TGFBRAP1 Products)
- Synonyms
- TRAP-1 Protein, TRAP1 Protein, 3110018K12Rik Protein, AU024090 Protein, AU042859 Protein, AW742551 Protein, Trap1 Protein, zgc:162302 Protein, transforming growth factor beta receptor associated protein 1 Protein, transforming growth factor, beta receptor associated protein 1 Protein, TGFBRAP1 Protein, tgfbrap1 Protein, Tgfbrap1 Protein
- Background
- TGFBRAP1 plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. It may recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2. Recombinant human TGFBRAP1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 33 kDa (296aa)
- NCBI Accession
- NP_004248
- UniProt
- Q8WUH2
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