DOK4 Protein (AA 1-326) (His tag)
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- Target See all DOK4 Proteins
- DOK4 (Docking Protein 4 (DOK4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-326
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DOK4 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMATNFSD IVKQGYVKMK SRKLGIYRRC WLVFRKSSSK GPQRLEKYPD EKSVCLRGCP KVTEISNVKC VTRLPKETKR QAVAIIFTDD SARTFTCDSE LEAEEWYKTL SVECLGSRLN DISLGEPDLL APGVQCEQTD RFNVFLLPCP NLDVYGECKL QITHENIYLW DIHNPRVKLV SWPLCSLRRY GRDATRFTFE AGRMCDAGEG LYTFQTQEGE QIYQRVHSAT LAIAEQHKRV LLEMEKNVRL LNKGTEHYSY PCTPTTMLPR SAYWHHITGS QNIAEASSYA GEGYGAAQAS SETDLLNRFI LLKPKPSQGD SSEAKTPSQ
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product DOK4 Protein
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Docking Protein 4 (DOK4) (AA 1-326) protein (GST tag)
DOK4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Docking Protein 4 (DOK4) (AA 1-326) protein (Strep Tag)Crystallography grade DOK4 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Docking Protein 4 (DOK4) (AA 1-325) protein (Strep Tag)Crystallography grade DOK4 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Docking Protein 4 (DOK4) protein (His tag)DOK4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- DOK4 (Docking Protein 4 (DOK4))
- Alternative Name
- DOK4 (DOK4 Products)
- Synonyms
- DOK4 Protein, docking protein 4 Protein, DOK4 Protein, Dok4 Protein
- Background
- DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. This protein is putative link with downstream effectors of RET in neuronal differentiation. DOK4 may be involved in the regulation of the immune response induced by T-cells. Recombinant human DOK4 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 39.4kDa (349aa)
- NCBI Accession
- NP_060580
- UniProt
- Q8TEW6
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