ICAM2 Protein (AA 22-223) (His tag)
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- Target See all ICAM2 Proteins
- ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-223
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ICAM2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSSDEKVFE VHVRPKKLAV EPKGSLEVNC STTCNQPEVG GLETSLDKIL LDEQAQWKHY LVSNISHDTV LQCHFTCSGK QESMNSNVSV YQPPRQVILT LQPTLVAVGK SFTIECRVPT VEPLDSLTLF LFRGNETLHY ETFGKAAPAP QEATATFNST ADREDGHRNF SCLAVLDLMS RGGNIFHKHS APKMLEIYEP VSDSQ
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ICAM2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
- Alternative Name
- ICAM2 (ICAM2 Products)
- Synonyms
- ICAM2 Protein, CD102 Protein, Icam-2 Protein, Ly-60 Protein, intercellular adhesion molecule 2 Protein, LOC506088 Protein, ICAM2 Protein, LOC616254 Protein, LOC100140873 Protein, Icam2 Protein
- Background
- ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. Recombinant human ICAM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 24.8 kDa (225aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_001093259
- UniProt
- P13598
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