CFP Protein (AA 28-469) (His tag)
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- Target See all CFP Proteins
- CFP (Complement Factor P (CFP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-469
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CFP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSDPVLCFT QYEESSGKCK GLLGGGVSVE DCCLNTAFAY QKRSGGLCQP CRSPRWSLWS TWAPCSVTCS EGSQLRYRRC VGWNGQCSGK VAPGTLEWQL QACEDQQCCP EMGGWSGWGP WEPCSVTCSK GTRTRRRACN HPAPKCGGHC PGQAQESEAC DTQQVCPTHG AWATWGPWTP CSASCHGGPH EPKETRSRKC SAPEPSQKPP GKPCPGLAYE QRRCTGLPPC PVAGGWGPWG PVSPCPVTCG LGQTMEQRTC NHPVPQHGGP FCAGDATRTH ICNTAVPCPV DGEWDSWGEW SPCIRRNMKS ISCQEIPGQQ SRGRTCRGRK FDGHRCAGQQ QDIRHCYSIQ HCPLKGSWSE WSTWGLCMPP CGPNPTRARQ RLCTPLLPKY PPTVSMVEGQ GEKNVTFWGR PLPRCEELQG QKLVVEEKRP CLHVPACKDP EEEEL
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product CFP Protein
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Complement Factor P (CFP) (AA 213-334) protein (GST tag)
CFP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Complement Factor P (CFP) (AA 1-469) protein (GST tag)CFP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Complement Factor P (CFP) (AA 28-469) protein (His tag)Crystallography grade CFP Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Complement Factor P (CFP) (AA 23-464) protein (His tag)Crystallography grade CFP Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- CFP (Complement Factor P (CFP))
- Alternative Name
- CFP (CFP Products)
- Synonyms
- BFD Protein, PFC Protein, PFD Protein, PROPERDIN Protein, BCFG Protein, Pfc Protein, Properdin Protein, complement factor properdin Protein, CFP Protein, Cfp Protein
- Background
- CFP is a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified. Recombinant human CFP protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 50.9 kDa (465aa)
- NCBI Accession
- NP_002612
- UniProt
- P27918
- Pathways
- Complement System
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