PRKRA Protein (AA 1-313) (His tag)
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- Target See all PRKRA Proteins
- PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-313
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PRKRA protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMSQSRHR AEAPPLERED SGTFSLGKMI TAKPGKTPIQ VLHEYGMKTK NIPVYECERS DVQIHVPTFT FRVTVGDITC TGEGTSKKLA KHRAAEAAIN ILKANASICF AVPDPLMPDP SKQPKNQLNP IGSLQELAIH HGWRLPEYTL SQEGGPAHKR EYTTICRLES FMETGKGASK KQAKRNAAEK FLAKFSNISP ENHISLTNVV GHSLGCTWHS LRNSPGEKIN LLKRSLLSIP NTDYIQLLSE IAKEQGFNIT YLDIDELSAN GQYQCLAELS TSPITVCHGS GISCGNAQSD AAHNALQYLK IIAERK
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product PRKRA Protein
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Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (AA 1-313) protein (GST tag)
PRKRA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (AA 101-200) protein (GST tag)PRKRA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (AA 1-313) protein (Strep Tag)Crystallography grade PRKRA Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (AA 1-313) protein (Strep Tag)Crystallography grade PRKRA Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PRKRA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2 mM DTT, 1 mM EDTA
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))
- Alternative Name
- PRKRA (PRKRA Products)
- Synonyms
- PRKRA Protein, AV120107 Protein, PRK Protein, Pact Protein, RAX Protein, lear Protein, DYT16 Protein, PACT Protein, im:7151758 Protein, zgc:162619 Protein, dyt16 Protein, pact Protein, prkra-a Protein, prkra-b Protein, rax Protein, rbpa Protein, protein activator of interferon induced protein kinase EIF2AK2 Protein, protein kinase, interferon inducible double stranded RNA dependent activator Protein, protein kinase, interferon-inducible double stranded RNA dependent activator Protein, protein activator of interferon induced protein kinase EIF2AK2 L homeolog Protein, PRKRA Protein, Prkra Protein, prkra Protein, prkra.L Protein
- Background
- PRKRA is a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants. Recombinant human PRKRA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 36.8 kDa (336aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_003681
- UniProt
- O75569
- Pathways
- Regulatory RNA Pathways
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