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LOX Protein (AA 169-417) (His tag)

LOX Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN5853903
  • Target See all LOX Proteins
    LOX (Lysyl Oxidase (LOX))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 169-417
    Origin
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 7
    • 4
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This LOX protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSDDPYNPY KYSDDNPYYN YYDTYERPRP GGRYRPGYGT GYFQYGLPDL VADPYYIQAS TYVQKMSMYN LRCAAEENCL ASTAYRADVR DYDHRVLLRF PQRVKNQGTS DFLPSRPRYS WEWHSCHQHY HSMDEFSHYD LLDANTQRRV AEGHKASFCL EDTSCDYGYH RRFACTAHTQ GLSPGCYDTY GADIDCQWID ITDVKPGNYI LKVSVNPSYL VPESDYTNNV VRCDIRYTGH HAYASGCTIS PY
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product LOX Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Denatured

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    LOX (Lysyl Oxidase (LOX))
    Alternative Name
    LOX (LOX Products)
    Synonyms
    LOX Protein, Xlox Protein, MGC146507 Protein, lox Protein, zgc:77447 Protein, AI893619 Protein, TSC-160 Protein, H-rev142 Protein, Rrg1 Protein, lysyl oxidase Protein, lysyl oxidase a Protein, lysyl oxidase L homeolog Protein, LOX Protein, lox Protein, loxa Protein, lox.L Protein, Lox Protein
    Background
    LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. Recombinant human LOX protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Molecular Weight
    31.4 kDa (272aa)
    NCBI Accession
    NP_002308
    UniProt
    P28300
    Pathways
    SARS-CoV-2 Protein Interactome
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