GTF2H5 Protein (AA 1-71) (His tag)
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- Target See all GTF2H5 Proteins
- GTF2H5 (General Transcription Factor IIH, Polypeptide 5 (GTF2H5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-71
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GTF2H5 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMVNVLKG VLIECDPAMK QFLLYLDESN ALGKKFIIQD IDDTHVFVIA ELVNVLQERV GELMDQNAFS LTQK
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product GTF2H5 Protein
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General Transcription Factor IIH, Polypeptide 5 (GTF2H5) (AA 1-71) protein (GST tag)
GTF2H5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
General Transcription Factor IIH, Polypeptide 5 (GTF2H5) (AA 1-71) protein (Strep Tag)Crystallography grade GTF2H5 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
General Transcription Factor IIH, Polypeptide 5 (GTF2H5) (AA 1-71), (full length) protein (GST tag)GTF2H5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
General Transcription Factor IIH, Polypeptide 5 (GTF2H5) protein (Myc-DYKDDDDK Tag)GTF2H5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Liquid, In Phosphate buffered saline ( pH 7.4) containing 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- GTF2H5 (General Transcription Factor IIH, Polypeptide 5 (GTF2H5))
- Alternative Name
- GTF2H5 (GTF2H5 Products)
- Synonyms
- 2700017P07Rik Protein, 2810432H05Rik Protein, D17Wsu155e Protein, C6orf175 Protein, TFB5 Protein, TFIIH Protein, TGF2H5 Protein, TTD Protein, TTD-A Protein, TTDA Protein, bA120J8.2 Protein, RGD1560991 Protein, ttd Protein, tfb5 Protein, ttda Protein, ttd-a Protein, tgf2h5 Protein, ba120j8.2 Protein, si:dkey-12h9.4 Protein, zgc:153434 Protein, general transcription factor IIH, polypeptide 5 Protein, general transcription factor IIH subunit 5 Protein, Gtf2h5 Protein, GTF2H5 Protein, gtf2h5 Protein
- Background
- GTF2H5 is a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. Recombinant human GTF2H5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 10.4 kDa (94aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_997001
- UniProt
- Q6ZYL4
- Pathways
- DNA Damage Repair
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