SERPINB8 Protein (AA 1-374) (His tag)

Catalog No. ABIN5854005

Product Details

Target: SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))

Protein Type: Recombinant

Protein Characteristics: AA 1-374

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SERPINB8 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDDLCEA NGTFAISLFK ILGEEDNSRN VFFSPMSISS ALAMVFMGAK GSTAAQMSQA LCLYKDGDIH RGFQSLLSEV NRTGTQYLLR TANRLFGEKT CDFLPDFKEY CQKFYQAELE ELSFAEDTEE CRKHINDWVA EKTEGKISEV LDAGTVDPLT KLVLVNAIYF KGKWNEQFDR KYTRGMLFKT NEEKKTVQMM FKEAKFKMGY ADEVHTQVLE LPYVEEELSM VILLPDDNTD LAVVEKALTY EKFKAWTNSE KLTKSKVQVF LPRLKLEESY DLEPFLRRLG MIDAFDEAKA DFSGMSTEKN VPLSKVAHKC FVEVNEEGTE AAAATAVVRN SRCSRMEPRF CADHPFLFFI RHHKTNCILF CGRFSSP

Purity: > 95 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 30 % glycerol, 1  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))

Alternative Name: SERPINB8 (SERPINB8 Products)

Synonyms: pi8 Protein, cap2 Protein, CAP-2 Protein, CAP2 Protein, NK10 Protein, Spi8 Protein, ovalbumin Protein, PI8 Protein, serpin family B member 8 Protein, serpin B8 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 8 Protein, serine (or cysteine) peptidase inhibitor, clade B, member 8 Protein, Serpinb8 Protein, SERPINB8 Protein, LOC607205 Protein, serpinb8 Protein, LOC100424017 Protein

Background: The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. SERPINB8 is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1, is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position. Recombinant human SERPINB8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 45.2 kDa (397aa) confirmed by MALDI-TOF

NCBI Accession: NP_942130

UniProt: P50452