PICK1 Protein (AA 1-415) (His tag)
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- Target See all PICK1 Proteins
- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-415
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PICK1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMFADLDY DIEEDKLGIP TVPGKVTLQK DAQNLIGISI GGGAQYCPCL YIVQVFDNTP AALDGTVAAG DEITGVNGRS IKGKTKVEVA KMIQEVKGEV TIHYNKLQAD PKQGMSLDIV LKKVKHRLVE NMSSGTADAL GLSRAILCND GLVKRLEELE RTAELYKGMT EHTKNLLRAF YELSQTHRAF GDVFSVIGVR EPQPAASEAF VKFADAHRSI EKFGIRLLKT IKPMLTDLNT YLNKAIPDTR LTIKKYLDVK FEYLSYCLKV KEMDDEEYSC IALGEPLYRV STGNYEYRLI LRCRQEARAR FSQMRKDVLE KMELLDQKHV QDIVFQLQRL VSTMSKYYND CYAVLRDADV FPIEVDLAHT TLAYGLNQEE FTDGEEEEEE EDTAAGEPSR DTRGAAGPLD KGGSWCDS
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product PICK1 Protein
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Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 1-415) protein (GST tag)
PICK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 266-375) protein (GST tag)PICK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 1-415) protein (Strep Tag)Crystallography grade PICK1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 1-416) protein (Strep Tag)Crystallography grade PICK1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 1-200), (partial) protein (GST tag)PICK1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) proteinPICK1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PICK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PICK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PICK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid, In Phosphate buffered saline ( pH 7.4) containing 30 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
- Alternative Name
- PICK1 (PICK1 Products)
- Synonyms
- PICK Protein, PRKCABP Protein, Prkcabp Protein, prkcabp Protein, MGC131295 Protein, PICK1 Protein, DKFZp470L2127 Protein, protein interacting with PRKCA 1 Protein, protein interacting with C kinase 1 Protein, protein interacting with PRKCA 1 L homeolog Protein, PICK1 Protein, Pick1 Protein, pick1 Protein, pick1.L Protein
- Background
- PICK1 contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. PICK1 has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Recombinant human PICK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 49.0 kDa (438aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI Accession
- NP_001034673
- UniProt
- Q9NRD5
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