IL12RB1 Protein (AA 1-545) (His tag)
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- Target See all IL12RB1 Proteins
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-545
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IL12RB1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMEPLVTW VVPLLFLFLL SRQGAACRTS ECCFQDPPYP DADSGSASGP RDLRCYRISS DRYECSWQYE GPTAGVSHFL RCCLSSGRCC YFAAGSATRL QFSDQAGVSV LYTVTLWVES WARNQTEKSP EVTLQLYNSV KYEPPLGDIK VSKLAGQLRM EWETPDNQVG AEVQFRHRTP SSPWKLGDCG PQDDDTESCL CPLEMNVAQE FQLRRRQLGS QGSSWSKWSS PVCVPPENPP QPQVRFSVEQ LGQDGRRRLT LKEQPTQLEL PEGCQGLAPG TEVTYRLQLH MLSCPCKAKA TRTLHLGKMP YLSGAAYNVA VISSNQFGPG LNQTWHIPAD THTEPVALNI SVGTNGTTMY WPARAQSMTY CIEWQPVGQD GGLATCSLTA PQDPDPAGMA TYSWSRESGA MGQEKCYYIT IFASAHPEKL TLWSTVLSTY HFGGNASAAG TPHHVSVKNH SLDSVSVDWA PSLLSTCPGV LKEYVVRCRD EDSKQVSEHP VQPTETQVTL SGLRAGVAYT VQVRADTAWL RGVWSQPQRF SIEVQVSD
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product IL12RB1 Protein
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Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) protein (His tag)
IL12RB1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) (Active) protein (Fc Tag,AVI tag,Biotin)IL12RB1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 1-381) protein (GST tag)IL12RB1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 592-738) protein (His tag)Crystallography grade IL12RB1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 20-565) protein (His tag)Crystallography grade IL12RB1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-662) protein (rho-1D4 tag)Crystallography grade IL12RB1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 20-738) protein (rho-1D4 tag)Crystallography grade IL12RB1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) (Active) protein (His tag)IL12RB1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) (Active) protein (Fc Tag)IL12RB1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM TRIS 8.0 buffer containing 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- Alternative Name
- IL12RB1 (IL12RB1 Products)
- Synonyms
- Il12rb Protein, IL12RB1 Protein, IL-12R Protein, CD212 Protein, IL-12R-BETA1 Protein, IL12RB Protein, IL-12R[b] Protein, interleukin 12 receptor subunit beta 1 Protein, interleukin 12 receptor, beta 1 Protein, Il12rb1 Protein, IL12RB1 Protein
- Background
- IL12RB1 is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Recombinant human IL12RB1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 62.6kDa (568aa)
- NCBI Accession
- NP_005526
- UniProt
- P42701
- Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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